TNFa (aka cachexin or cachectin) is a cytokine, which is a small protein / peptide that relays communication amongst cells.
It promotes insulin resistance and is associated with type2 diabetes. Macrophages secrete TNF to alert other cells about inflammation. TNF signals via 2 receptor types (1 & 2) and suppressing TNF1 is helpful for autoimmune diseases. TUMOR NECROSIS FACTOR (TNF OR TNFa) TNF parallels parathyroid hormone in causing hypercalcemia. TNF stimulates CRH , a stress hormone.
It promotes insulin resistance and is associated with type2 diabetes. Macrophages secrete TNF to alert other cells about inflammation. TNF signals via 2 receptor types (1 & 2) and suppressing TNF1 is helpful for autoimmune diseases. TUMOR NECROSIS FACTOR (TNF OR TNFa) TNF parallels parathyroid hormone in causing hypercalcemia. TNF stimulates CRH , a stress hormone.
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